Composition

Each gram contains

Ciprofloxacin ……..100mg

Pharmacological action

Ciprofloxacin is a bacteriostatic at low concentration and bactericidal at high concentration. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Ciprofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.

Indication

Ciprofloxacin is a broad-spectrum antibiotic that is active against Cram-positive.

Gram-negative bacteria, Myco plasma infection, Ecoli, Salmonella, Anaerobic bacterobic infection and Streptocossus, etc.

It is used for treatment of bacterial infection and Myco plasma infection in Poultry.

Dosage and Administration

Calucated by this product

Mix with water ,for eahc liter

Poultry: 0.4-0.8 g(equals to ciprofloxacin 40-80mg .)

Twice a day for three days.

Withdrawal period

Meat: 3 days

Storage

Store below 30 centigrade cool dry place and avoid light