Amoxicillin soluble powder 30%

Composition

Each g contains

Amoxicillin…….300mg

Pharmcology action

Amoxicillin Anhydrous is the anhydrous form of a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Amoxicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.

Indications

Gastrointestinal, respiratory and urinary tract infections caused by amoxycillin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.

Contra indications

Hypersensitivity to amoxycillin. Administration to animals with a serious impaired renal function. Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides. Administration to animals with an active microbiological digestion.

Side effects

Hypersensitivity reaction.

Dosage

For oral administration:

Calves, goats and sheep  :

Twice daily 8 gram per 100 kg. body weight for 3 – 5 days.

Poultry and swine:

1 kg. per 600 - 1200 litre drinking water for 3 – 5 days.

Note: for pre-ruminant calves, lambs and kids only.

Withdrawal times

For meat:

Calves, goats, sheep and swine  8 days.

Poultry  3 days.

Warning

Keep out of reach of children.