Cefquinome Sulphate injection
Cefquinome is a semisynthetic, broad-spectrum, fourth-generation aminothiazolyl cephalosporin with antibacterial activity. Cefquinome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
This product is used in treatment of respiratory tract infections (particularly caused by penicillin-resistant bacteria), foot infections (foot rot, pododermatitis) caused by cefquinome-sensitive bacteria in cattle with viral diseases.
It is also used in treatment of the bacterial infections that occur in thelungs and respiratory tract of swine, which is mainly caused by Mannheimia hemolytica, Haemophilus parasuis, Actinobacillus pleuropneumoniae, Streptococcus suis and other cefquinome-sensitive organisms and additionally it is used in the treatment of Mastitis- metritis-agalactia syndrome (MMA) with involvement of E.coli, Staphylococcus spp.,
Administration and Dosage:
Pigs: 2 ml/ 25 kg of body weight. Once a day for 3 consecutive days (IM)
Piglet: 2 ml/ 25 kg of body weight. Once a day for 3 -5 consecutive days (IM)
Calves, foals: 2 ml/ 25 kg of body weight. Once a day foe 3 – 5 consecutive days (IM)
Cattle, horses: 1 ml / 25 kg of body weight. Once a day for 3 – 5 consecutive days (IM).
Cattle: 5 days; Pigs: 3 days.
Milk: 1 day
Storage: Store at room temperature, keep sealed.
Package: 50ml ,100ml vial.